This study aims to define the interests and goals of the United States in the Arab region by answering two main questions: how does the Obama administration differ from its predecessors in view of its promises of change, particularly following the tragic transformations raging in the Arab region at present? And to what extent does the strategy of this administration reflect its public diplomacy regarding democracy, freedom, and justice in the region? The study explains how Obama raised the ceiling of expectations when he did not limit his promises to a change in American policy only, but included putting an end to the mentality that had pushed the United States into war. Despite the difference in style and method between the Obama and Bush Junior administrations, the overall goals and the regional strategy can be summarized in terms of three key interests: the priority of ensuring free access to energy supplies in the region; maintaining American supremacy over all other global powers; and the containment of all Arab objections to ensure the dominance of the US strategic agenda in the Arab region, including the guarantee of Israel's security.