This paper presents an overview of Arab public opinion towards US policies in the Arab region at a turning point between two US administrations. The findings, taken from the 2016 Arab Opinion Index, show that the Arab public has a complete lack of trust in US policies towards their region. The paper explores the evolution of Arab public perceptions of US policies through successive polls of the Arab Opinion Index, and analyzes the factors driving negative Arab public perceptions of US foreign policy in the region, asking whether these are driven by religious, cultural, political or ideological reasons. With the Obama Administration handing over to Trump, the author examines the Arab public expectations of a change US foreign policy towards the region.