Sudanese President Omar al-Bashir’s call for national dialogue marks a critical turning point in the nation’s recent politics. This paper presents the conditions that led to Bashir’s call for the first time after his nearly 25-year rule, and describes the serious and genuine nature of this call, as well as the positions of the opposing parties. It then goes on to explain some of the challenges that might hinder the success of Bashir’s call for dialogue, in particular the extent of concessions that president Bashir and his ruling party will have to make in order for the dialogue to be successful. It further examines the extent of the flexibility that the civil and armed oppositions should maintain if this last opportunity is not to be missed to save the country from falling into a state of turmoil. This internal Sudanese situation is read within the context of the regional and international conflicts that impact the call for dialogue. Finally, the paper sets out the possible negative and positive impacts of the international situation regarding the possibility of Sudan’s recovery from its current deteriorating situation.